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DPX-R 6447

azafenidin

CAS: 68049-83-2

Molecular Formula: C15H13Cl2N3O2

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DPX-R 6447 - Names and Identifiers

Name azafenidin
Synonyms Evolus
R 6447
Milestone
IN-R 6447
azafenidin
DPX-R 6447
2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazole(4,3-a)pyridin-3(2H)-one
2-(2,4-dichloro-5-prop-2-ynyloxypnenyl)-5,6,7,8-tetrahy-dro-1,2,4-trizolo [4,3-α] pyridin-3-(2H)-one
CAS 68049-83-2

DPX-R 6447 - Physico-chemical Properties

Molecular FormulaC15H13Cl2N3O2
Molar Mass338.19
Density1.43±0.1 g/cm3(Predicted)
Melting Point168-168.5°
Boling Point468.9±55.0 °C(Predicted)
Physical and Chemical PropertiesThe pure chemical product is a solid with a strong smell of rust color. M. p.168 ~ 168.5 ℃, relative density 1.4 (20 ℃), vapor pressure 1 × 10-9Pa (25 ℃), solubility in water 12mg/L (pH = 7). The distribution coefficient is 2.7, stable to hydrolysis, and the half-life of light in water is about 12d.
UseUses triazolinone herbicides, protoporphyrinogen oxidase inhibitors. Suitable for Olive, citrus, forest and non-crop and weed-growing sites. Control of many important weeds, such as broad-leaved weeds purslane, Portulaca oleracea, Chenopodium, mustard, senecio, Solanum nigrum, etc.; Gramineae weeds such as green grass, Maldon, Poa pratensis, Humulus, etc. It has special effects on weeds producing antibodies such as triazobenzene, aryloxycarboxylic acid lamps, cyclohexanediones and ALS inhibitors such as sulfonylurea herbicides. Application before the emergence of weeds, the dose of 240g active ingredient/hm2.

DPX-R 6447 - Risk and Safety

Risk CodesR61 - May cause harm to the unborn child
R48/22 - Harmful danger of serious damage to health by prolonged exposure if swallowed.
R62 - Possible risk of impaired fertility
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
Safety DescriptionS53 - Avoid exposure - obtain special instructions before use.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60 - This material and its container must be disposed of as hazardous waste.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. 

DPX-R 6447 - Upstream Downstream Industry

Raw Materials2,4-Dichlorophenol
Erythromycin Estolate
(-)-MENTHYL CHLOROFORMATE

DPX-R 6447 - Nature

acidity coefficient (pKa) 2.45±0.20(Predicted)
EPA chemical information Azafeniden (68049-83-2)
Last Update:2024-04-10 22:29:15

DPX-R 6447 - Uses and synthesis methods

Toxicity

acute oral LD50>5000mg/kg in rats, acute percutaneous LD50>2000mg/kg in rabbits, and acute inhalation of LC50 in rats was 5.3mg/L. No irritation to rabbit eyes and skin. Ames test negative, no mutagenicity. The LC50 was 48mg/L (96h) for the big sunfish, 33mg/L (96h) for the rainbow trout and 38mg/L (48h) for the Daphnia.

production method

2, 4-dichlorophenol is made by etherification, nitration, and reduction to obtain the corresponding intermediate, and then diazotization and reduction to obtain the corresponding substituted phenylhydrazine; cyanoprene carbamate reacts with acetic anhydride to obtain the corresponding intermediate. The two intermediate products react and then heat the ring to prepare zolidinone.

Last Update:2024-04-10 22:29:15

DPX-R 6447 - Security information

Toxicity

LD50 in rats, mice, bobwhite quail, mallard duck (mg/kg): >5000, >5000, >2500, >2500 orally; in rabbits (mg/kg): >2000 dermally.; LC50 in rats, rainbow trout, blue gill sunfish (mg/l): >5.3, 33, 48 (Amuti)

Last Update:2024-04-10 22:29:15
DPX-R 6447
Supplier List
Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: Azafenidin Request for quotation
CAS: 68049-83-2
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Azafenidin Request for quotation
CAS: 68049-83-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Azafenidin Visit Supplier Webpage Request for quotation
CAS: 68049-83-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: Azafenidin Request for quotation
CAS: 68049-83-2
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Azafenidin Request for quotation
CAS: 68049-83-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Azafenidin Visit Supplier Webpage Request for quotation
CAS: 68049-83-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
DPX-R 6447
Raw Materials for DPX-R 6447
2,4-Dichlorophenol
Erythromycin Estolate
(-)-MENTHYL CHLOROFORMATE
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